Fibronectin anticorps

N° du produit ABIN6296126

L’anticorps Souris Monoclonal anti-Fibronectin a été validé pour IHC, IF et FACS. Il convient pour détecter Fibronectin dans des échantillons de Humain, Rat, Souris et Porc.

Aperçu rapide pour Fibronectin anticorps (ABIN6296126)

Antigène: Fibronectin

Reactivité: Humain, Rat, Souris, Porc

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Fibronectin est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-Fibronectin anticorps

Fonction: Mouse anti-Human/Pig/Mouse/Rat Fibronectin Antibody [Sodium Azide Free]

Specificité: Connective tissue matrix

Purification: A T-cell lymphoma biopsy was used as the immunogen for this fibronectin antibody.

Immunogène: A T-cell lymphoma biopsy was used as the immunogen for this fibronectin antibody.

Information d'application

Indications d'application: FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur Fibronectin

Antigène: Fibronectin

Sujet:

Target Description: Fibronectin is a soluble dimeric glycoprotein of 440 kDa, which is present in cells, extracellular matrix, and blood. There are two types of fibronectin: soluble fibronectin which is produced by hepatocytes and found in blood plasma, and insoluble cellular fibronectin which is produced by fibroblasts in a soluble form and latter assembled into an insoluble form via fibril formation.This antibody reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this antibody localizes to tumor vessels where it binds to the underlying basement. The Fibronectin epitope recognized by this antibody is not accessible in normal tissues to the circulating antibody indicating that it can be used to specifically target tumor vessels in vivo. Clone TV-1 fibronectin antibody is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or antibodies.

Gene Symbol: FN1///FN

ID gène: 2335

UniProt: P02751